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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccd7f9284096b116e8af8d5aed56d36d8d5006f68b3a2bb8e172e14bffc5e4f6' 
  AND token = 'CZ1WAZVJo0VuSih0lAZVyCPWL0SKTWVQkqqa3dQezEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}