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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6d59406bb84897b663cfa17b5ba10a1cdb64b195af750c9faba97827a09b708' 
  AND token = 'laI0M+XQbnrUV9skgl9jQhWqXYSFSIqvaC9JMsO19C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}