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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3ccaa89806f5a5f66e96ec337e3fde2da39a920a0f7440cdef90887e465e04c' 
  AND token = 'hulLdTTzFX9gEH+bHKY03uWSKNWFGGpB8cmW0/YHnuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}