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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db450e079bca6594c4044d7e6ed91488917c251278f8457553ad8ec8da4e4071' 
  AND token = 'kEQn4XJG+sz8khubF5re3/Zsj1xB0l1TZfX4XfHTohc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}