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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4437e7dda836ffcce85c0962de214be3d193475ff5e7e286a8a01cf244860a9f' 
  AND token = 'dNyAV6ecsYF+jfSvFdwPfo9r1fe/a+hHiM0PbfuG17Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}