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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b13326e3d6aa41f7f6f8cd2aa0532cc72851040a6b05370d1ba9d4042bd59337' 
  AND token = 'p6RZ8OgXpqpq0w13ik5IyalV+qmFnTdmQ6VcDwWZQ40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}