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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36d4226edd2eba2f759ddbec4fdb967927a19d79c973587f1b4f3b32594c93c0' 
  AND token = 'XiHL8mRODCruIPIxLx3Zb2oLEjmKtJtzBj6/C599Ww4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}