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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8452ce168fa4406752327c30a63f4f69f71b7552c76f6ca2f84638a37b1c5989' 
  AND token = 'Si4Ccp7n7PVWNkm3sNo/cCbsVyRmVSB3rNIE82kGLXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}