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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f946d2643db533bcb31848139e29d7fbd09b073f42b14ab4b48c0790cc6a6eb' 
  AND token = 'SRI1QHGH7/N3oS+orQcT7YzzHYFVapZIeZmCdCdSDdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}