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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48bf813f61e519158de62d00827a0e422a900307cca3fd42935c25b07ead484b' 
  AND token = 'MC2pj3kBREAKcX866lgS26WjW2nc+SU9HRyV1UaFzgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}