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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0541048f63154c4b65ef4fca611a8737cc8d00a4b10603d67bce0d401a71431' 
  AND token = 'j/6/P9rPuL3c3KhUPZQS6DdPCDROqEWwynsuZYbtYxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}