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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '517b9b3b002ccc6a2ad8660b93d2faae12b7f0dd65052c8a21dd272595c6bee1' 
  AND token = '5qP375/D3+DLNMn+vdbU0jOjzD2SnvOSfN39yi1uJkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}