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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a9222f9b3afe95dbcfc51ddd457a63a6061bb1d8c5515f951b94f0ed3079eb' 
  AND token = 'HgF8+Urcc7dl/GltkXdPdp6JYhZVmdE0y4lpIq156+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}