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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b320fdec0c0198a97e6712d433e50bf375218669470fe022d2f25795e87cb43c' 
  AND token = 'X2ZV1TwbACQQHHuEtnzPX5eake+rs+CQrkU/MpIJngQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}