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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a82b23e5485451a1fca288d095920b99d1750f97bc52f4a4aaf37ed45bb219d' 
  AND token = 'MLeF69x4guo35gvXETUk448x13ys/okufkuvijTOddQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}