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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c88dc0af1ce921cc3715e2230c420d3be69d78d4ad623c7f7fbdce070d8e2e1' 
  AND token = 'HohtH57Oiizxx5WovH1ULWojwrO+HCj85G+AzN0MZ84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}