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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eb5c3efa6538b839ad86dd7b7bbcc04ba98beface5053ee0113aa0b79b67653' 
  AND token = 'mE1ik+tMe9/YjtnAsCFCXObV9vIqwCWHcEwp0lHfyCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}