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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10aad0ea4c695e06b44fa49c490031f3435d9b466d5666b25749f41fdca7db02' 
  AND token = 'bQjSZ2DWjOEx4nXaJ35G60hjUT1Vkw2fi+mTU8siBQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}