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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e6810d87bf5fd94457d5976a27747c2ea662f75c53e13e68e4047755bd290d' 
  AND token = 'khgYkV/7EuiweMsrYzmS8XK9Rji3zfXn2IoM9PKt4f4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}