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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffd8237922cea2b2665d02c06a4e3c32e5f325ce0aac4750947d8f1296909f09' 
  AND token = 'njDS0MC+oREYAQfyJotmyMcaE8Q/VAy03WHUsk5Aw/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}