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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ce4463b80dd5e906c5a2452d1babe3aced931f25fc114b32ebee03cf0d43275' 
  AND token = 'vnDEeWg/S6JuNqRc4BEXEHzN/Y6yPvXVmZnbaoUXCjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}