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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb3fa08c64f7cec6763c574a8d12683b426371bbcf36eda972f74fc87488373' 
  AND token = 'U1nzpPWurkWbjBtJPaDQ1meQgdhzqY52J5Q0WlON7Y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}