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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64b5ca3c1ac26f265fe22cd0b72b361e3561890dda439f0d789a30be7036d1a9' 
  AND token = 'lwsecs7msRZ0SGDC7TOoaYjYuD+oQ+PKR1m3QsNb5iA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}