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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ec0e798614e350e78cc107dde79b44e2d69fd59c56876f6db462e5e2128446' 
  AND token = '9/QuV/p3IcrvRGzZoctVMjqi3oM5oK+rnxmHRKGy1x4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}