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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7a28216b11b10387d24a79fcb856ef0f76ef24365d1c599a4251ee890207891' 
  AND token = 'kxmR/hINWxhjmwxTsyy7TnvHZa4fL6lX0JTqRrrWGZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}