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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ab27182c0b536788fe6edf06f69ede46c89a043dc7ba50a859b519355bdb557' 
  AND token = 'vDGFJxc9PpC+PuMd2Qt7P9djLUMOgLwQLIxQcuBKQb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}