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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3601bb608147c75b2fdbf8f6166ee06bf72e444d3a75f9bbf8011a39ce4e1c1' 
  AND token = '/JeCQxS1b811uftqHuhfd52fH/joPgWHBe6Yi4Emoj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}