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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c780554dbc314e1078a79dbda3c352d480dd8504e99555cf7e524ffe5d5133' 
  AND token = 'SsBUwN1BuMoUsYOEw4VCR7O0JLIx+UtEsy6PSUapbNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}