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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '740bdce49b514a9858e6cfe8e3868c2a03463e01fd439fd37abceab5a036b956' 
  AND token = '+b67sq8WNrZRtXzUj0Rua6Daj3liJd/9f0ultxm3MDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}