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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c99e13771373bcf713542b654b6a7fe5334a8ec28540ea42b2160e7334b2f890' 
  AND token = 'RTuRgF5sJ1UUn5V0uVIJ4splAxM15kVzukLI+CN+rvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}