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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7d9e6856497d60102a68588a00d8a8e06f54f4027a084eb881f4b1b1d718610' 
  AND token = 'AYjICmT06lctnfsWi7uda0noHSJG1TTY6rrm1hFhr0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}