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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af2ba7cb14573f4eb8413ccaf8d4f2492a4116753a0feb4f07c034210a8ce647' 
  AND token = '48HiwvWjw7G+MM+5QNO4Ut4Fr6Hbfzgc3WHb4PeMehM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}