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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4993cd3e8bc08dfadfde908f514e73c84cc937f0a74b06bb212efd193fdd0f81' 
  AND token = 'hLmP1eqrSKxeNkrtqUyBuf8PqA30Pf+cOAXPvE3oCvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}