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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '533cd9be97e9953d0870f106e071da4eeb2b0b80e561228cace7aec68f1eaf80' 
  AND token = 'dFrRfz5v2cHNI2hJLc9x7lkIWg3G6/Vw1WuC9EacB/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}