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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc305ec02ffe47c1b0080354268f010bb113068e5f722cab256476b757d2b25d' 
  AND token = 'YpuF3TQrwGon4vv1tXhJwl6gMDKU913YlcKErSLEuPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}