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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28840d967adaa14be66b90492e315925bb9b94776ad0a5e014c7e72977a02286' 
  AND token = 'VI2hqvdXnopHLWr49M5EY21l39Cx+fJcIAxvXTZ5je0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}