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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5442adf55461300d135026e87609f49aff3e78b5cd06db5d1b1c186f82b44791' 
  AND token = '9EcaxxU90SqVCW2iV2F/eZfw6GHenIbNqHnVBB4axRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}