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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cce21a3228341bae528c1258181f84c60dfba6396a796db5f69ee7b640054961' 
  AND token = 'vRfC6DrJoQV0cu5asYezR+Tfa5smon1LTVG4s2qYXFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}