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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b142dd1def7e9b6d3dd80980c6ea32f95f1bf5518cc24fd7e36d96a9409e941' 
  AND token = '6XogdAgj9uLot9aak+U2jUd0P2GAgflLcY05trZnBME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}