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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9ac4686d67a5bbba6720ac1bad61f40c37dd1965a32461b854ab82e221dcfb3' 
  AND token = 'pn3gG9y0CpykBUjhTFkVcmUS27pPi1ZtQ7HlW+jAZLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}