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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '461e57f26e49ffc2c525819d808d68685f71e3f24e0b0e420deaf4df66780cf6' 
  AND token = 'bm5xSCMsv/SqKc+TNrXlHkQhg3sz25+yqaU06LsLZgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}