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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b75739ec71d875c6f719bec60912ff6c0b0b2730800c6fc282f9d14cc7c09465' 
  AND token = 'wnRMSKFVQoOAqI324FRRfbaPJT5SmKKEvAPlZ36X9zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}