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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4151f8452b6f5d22d64256a374c2c0906182f62a7a6e6e81694a2318b4b6c84c' 
  AND token = 'kHZsViYbR1+trvBlNwzK8s0XB06EEQxWV8ydz4AfW0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}