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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486d12d6aa35e569d90708f5f5a4c8f2c86c062b6272fe4590c340d9c704e7a4' 
  AND token = 'R9yGxeQHWpO2H9VfwQk5HLuG6LLnboGff/ViMvJ69k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}