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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b2ba54786c8268d1a5d62361c5f8d0d67f367051d5fe3bd954eba6a551d603' 
  AND token = 'n9BJS/VJco/MRwPq+tlo1oRiQQ2mDbr36DwUVqlsubE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}