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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38f0839396f9cba488e6b440a3c4fe618338b6d023aa3b2fb53e7842a0d4dac1' 
  AND token = 'eLYwbP9fONfRzeMpqsX1PfrfyoD7XEVdwe1o9DCY9RE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}