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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0caefdc7f62210f8e3f0b9d7280ac3f69d1f5810b7876d70c706ba415aae3781' 
  AND token = 'mzEGRDoRE3mVoA+KNcllV6/AaLnbDCdLrnPUZH4w6TQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}