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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4101fcdef0c71f3a7a0de1fcb1fe00090fd82b5d0941d02ff51f928d0ade9ae' 
  AND token = 'JPm4Yo2/wPZpNbJpw8zxzkfhfj7oX8pIF9nP/E9c2rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}