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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ddac7902994dc86416ee3e13196cbb6b01567827aecc9c7eb8bf56ef6285fb' 
  AND token = 'V2B5I6PbMrIXtXCVuy2Sg+8BKBbC/5Xu/DLsCMZaFPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}