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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd783ad91822a7f62fa7e6b038d1067b9a8a20faaed28f75b6fcc52110e8204d6' 
  AND token = 'fzIxIGhHo3U2bFWnXTn+Qd3VqDklAX9tdGdFi7PVfb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}